Millipore Sigma Vibrant Logo

MAB1687 Anti-Vimentin Antibody, clone 43BE8

MAB1687
100 µL  
Retrieving price...
Price could not be retrieved
Minimum Quantity is a multiple of
Maximum Quantity is
Upon Order Completion More Information
You Saved ()
 
Request Pricing
Limited Availability
Limited Availability
Stocked 
Discontinued
Limited Quantities Available
Available
    Remaining : Will advise
      Remaining : Will advise
      Will advise
      Contact Customer Service
      Contact Customer Service

      Special Offers

       

      Contact Customer Service

      Overview

      Replacement Information

      Key Specifications Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      H, MkICC, IH(P)MAscitesMonoclonal Antibody
      Description
      Catalogue NumberMAB1687
      Brand Family Chemicon®
      Trade Name
      • Chemicon
      DescriptionAnti-Vimentin Antibody, clone 43BE8
      References
      Product Information
      FormatAscites
      PresentationLiquid
      Quality LevelMQ100
      Applications
      ApplicationThis Anti-Vimentin Antibody, clone 43BE8 is validated for use in IC, IH(P) for the detection of Vimentin.
      Key Applications
      • Immunocytochemistry
      • Immunohistochemistry (Paraffin)
      Application NotesImmunohistochemistry: 1:500-1:2,000 on paraffin embedded sections (ABC peroxidase) fixed with alcohol (e.g. Carnoy) with a 2" pronase digestion. Aldehyde fixation is not recommended.

      Immunocytochemistry: 1:100-1:200 cells in vitro (IFA) fixed in ice cold absolute methanol or acetone.

      Optimal working dilutions must be determined by the end user.
      Biological Information
      Clone43BE8
      HostMouse
      SpecificityVimentin (58kD). Reacts in immunocytochemical assays with all mesenchymal cells (fibroblasts, Scwann cells, endothelial cells, smooth muscle cells, etc.).
      IsotypeIgM
      Species Reactivity
      • Human
      • Monkey
      Antibody TypeMonoclonal Antibody
      Entrez Gene Number
      Entrez Gene SummaryAlong with the microfilaments (actins) and microtubules (tubulins), the intermediate filaments represent a third class of well-characterized cytoskeletal elements. The subunits display a tissue-specific pattern of expression. Desmin (MIM 125660) is the subunit specific for muscle and vimentin the subunit specific for mesenchymal tissue.[supplied by OMIM]
      Gene Symbol
      • VIM
      • FLJ36605
      • Vimentin.
      • vimentin
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: P08670 # Vimentins are class-III intermediate filaments found in various non-epithelial cells, especially mesenchymal cells.
      SIZE: 466 amino acids; 53652 Da
      SUBUNIT: Homopolymer. Component of a complex composed at least of ACTB, AP2M1, AP2A1, AP2A2, MEGF10 and VIM. Interacts with HCV core protein.
      TISSUE SPECIFICITY: Highly expressed in fibroblasts, some expression in T- and B-lymphocytes, and little or no expression in Burkitt's lymphoma cell lines. Expressed in many hormone- independent mammary carcinoma cell lines.
      PTM: One of the most prominent phosphoproteins in various cells of mesenchymal origin. Phosphorylation is enhanced during cell division, at which time vimentin filaments are significantly reorganized.
      SIMILARITY: SwissProt: P08670 ## Belongs to the intermediate filament family.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsMaintain at -20°C in undiluted aliquots for up to 12 months. Avoid repeated freeze/thaw cycles.
      Packaging Information
      Material Size100 µL
      Transport Information
      Supplemental Information
      Specifications

      Related Products & Applications

      Related Products

      Catalog Number Description  
      AB1620 Anti-Vimentin Antibody Show Pricing & Availability
      AB5733 Anti-Vimentin Antibody Show Pricing & Availability
      CBL202 Anti-Vimentin Antibody, clone VIM 3B4 Show Pricing & Availability
      MAB1681 Anti-Vimentin Antibody, clone LN-6 Show Pricing & Availability
      MAB3400 Anti-Vimentin Antibody, clone V9 Show Pricing & Availability

      Product Families

      Categories

      Life Science Research > Antibodies and Assays > Primary Antibodies