05-559 Anti-Tubulin βIII Antibody, clone 2G10, neuronal

05-559
200 µg  
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      Overview

      Replacement Information

      Key Specifications Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      B, H, M, R WB, ICC M Purified Monoclonal Antibody
      Description
      Catalogue Number05-559
      Replaces04-1049
      Brand Family Upstate
      Trade Name
      • Upstate
      DescriptionAnti-Tubulin βIII Antibody, clone 2G10, neuronal
      References
      Product Information
      FormatPurified
      PresentationPBS, pH 7.4, 0.05% sodium azide before the addition of glycerol to 30%
      Quality LevelMQ100
      Applications
      ApplicationAnti-Tubulin βIII Antibody, clone 2G10, neuronal is an antibody against Tubulin βIII for use in WB & IC.
      Key Applications
      • Western Blotting
      • Immunocytochemistry
      Biological Information
      ImmunogenPeptide corresponding to residues 436-450 of neuronal specific βIII tubulin; epitope mapped to EAQGPK
      Cloneclone 2G10
      HostMouse
      Specificityneuronal specific βIII tubulin
      IsotypeIgG2a
      Species Reactivity
      • Bovine
      • Human
      • Mouse
      • Rat
      Antibody TypeMonoclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • TUBB3
      • TUBB4
      • beta-4
      • MC1R
      Purification MethodProtein G Chromatography
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: Q13509 # Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha-chain.
      SIZE: 450 amino acids; 50433 Da
      SUBUNIT: Dimer of alpha and beta chains.
      DOMAIN:SwissProt: Q13509 The highly acidic C-terminal region may bind cations such as calcium.
      SIMILARITY: Belongs to the tubulin family.
      Molecular Weight50kDa
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality Assuranceroutinely evaluated by immunoblot on RIPA lysates from PC12 cells
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage Conditions2 years at -20°C
      Packaging Information
      Material Size200 µg
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      Anti-Tubulin βIII Antibody, clone 2G10, neuronal SDS

      Title

      Safety Data Sheet (SDS) 

      Anti-Tubulin βIII Antibody, clone 2G10, neuronal Certificates of Analysis

      TitleLot Number
      Anti-Tubulin, clone 2G10, neuronal (mouse monoclonal IgG2a) - 21370872137087
      Anti-Tubulin, clone 2G10, neuronal (mouse monoclonal IgG2a)3083072
      Anti-Tubulin, clone 2G10, neuronal (mouse monoclonal IgG2a)3124165
      Anti-Tubulin, clone 2G10, neuronal (mouse monoclonal IgG2a)3017570
      Anti-Tubulin, clone 2G10, neuronal (mouse monoclonal IgG2a) - 20410262041026
      Anti-Tubulin, clone 2G10, neuronal (mouse monoclonal IgG2a) - 22971862297186
      Anti-Tubulin, clone 2G10, neuronal - 1945819458
      Anti-Tubulin, clone 2G10, neuronal - 2414224142
      Anti-Tubulin, clone 2G10, neuronal - 2660326603
      Anti-Tubulin, clone 2G10, neuronal - 3153931539

      References

      Reference overviewApplicationPub Med ID
      Expression and cellular localization of hepcidin mRNA and protein in normal rat brain.
      Raha-Chowdhury, R; Raha, AA; Forostyak, S; Zhao, JW; Stott, SR; Bomford, A
      BMC neuroscience  16  24  2015

      Show Abstract
      25896789 25896789
      The systemic iron-regulatory proteins hepcidin and ferroportin are reduced in the brain in Alzheimer's disease.
      Raha, AA; Vaishnav, RA; Friedland, RP; Bomford, A; Raha-Chowdhury, R
      Acta neuropathologica communications  1  55  2013

      Show Abstract
      24252754 24252754
      Enhanced aggregation of androgen receptor in induced pluripotent stem cell-derived neurons from spinal and bulbar muscular atrophy.
      Nihei, Y; Ito, D; Okada, Y; Akamatsu, W; Yagi, T; Yoshizaki, T; Okano, H; Suzuki, N
      The Journal of biological chemistry  288  8043-52  2013

      Show Abstract
      Immunofluorescence23364790 23364790
      Altered phosphorylation and distribution status of vimentin in rat seminiferous epithelium following 17β-estradiol treatment.
      Upadhyay, Rahul, et al.
      Histochem. Cell Biol., 136: 543-55 (2011)  2011

      Show Abstract
      21915674 21915674
      FGF-2 deficiency does not influence FGF ligand and receptor expression during development of the nigrostriatal system.
      Ratzka, A; Baron, O; Grothe, C
      PloS one  6  e23564  2011

      Show Abstract
      21876757 21876757
      Ubiquitination acutely regulates presynaptic neurotransmitter release in mammalian neurons.
      Gina V Rinetti,Felix E Schweizer
      The Journal of neuroscience : the official journal of the Society for Neuroscience  30  2010

      Show Abstract Full Text Article
      20203175 20203175
      Disruption of tubulobulbar complex by high intratesticular estrogens leading to failed spermiation.
      D'Souza, Ryan, et al.
      Endocrinology, 150: 1861-9 (2009)  2009

      Show Abstract
      19095743 19095743
      Increased cortical expression of two synaptogenic thrombospondins in human brain evolution.
      Cáceres, M; Suwyn, C; Maddox, M; Thomas, JW; Preuss, TM
      Cerebral cortex (New York, N.Y. : 1991)  17  2312-21  2007

      Show Abstract
      17182969 17182969
      Spatially and temporally specific expression in mouse hippocampus of Usp9x, a ubiquitin-specific protease involved in synaptic development.
      Jun Xu, Shinichiro Taya, Kozo Kaibuchi, Arthur P Arnold
      Journal of neuroscience research  80  47-55  2005

      Show Abstract
      15723417 15723417
      Sexually dimorphic expression of Usp9x is related to sex chromosome complement in adult mouse brain.
      J Xu, S Taya, K Kaibuchi, A P Arnold
      The European journal of neuroscience  21  3017-22  2005

      Show Abstract
      15978012 15978012

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