574597 Anti-Superoxide Dismutase (Cu/Zn Enzyme) Sheep pAb

574597
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Overview

Replacement Information

Key Specifications Table

Species ReactivityHostAntibody Type
H, Mk, M, R Sh Polyclonal Antibody

Pricing & Availability

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574597-1ML
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      Description
      OverviewRecognizes Cu/Zn SOD in red blood cells. Does not cross-react with Mn SOD.
      Catalogue Number574597
      Brand Family Calbiochem®
      SynonymsAnti-SOD
      References
      ReferencesPasinelli, P., et al. 1998. Proc. Natl. Acad. Sci. USA 95, 15763.
      Product Information
      FormLiquid
      FormulationIn glycine-buffered saline, pH 7.4.
      Positive controlHuman red blood cell lysate
      Preservative≤0.1% sodium azide
      Quality LevelMQ100
      Applications
      Key Applications Immunoelectrophoresis
      Paraffin Sections
      Free-floating Sections
      Frozen Sections
      Immunoblotting (Western Blotting)
      Application NotesImmunoblotting (1:1000)
      Immunoelectrophoresis (see comments)
      Frozen sections (see comments)
      Paraffin sections (see comments)
      Free-floating sections (see comments)
      Application CommentsThis antibody is monospecific as determined by immunoelectrophoresis against human red blood cell lysate and confirmed by immunodiffusion against a human red blood cell lysate and a known anti-SOD (Cu/Zn) antibody. Does not exhibit cross-reactivity with SOD (Mn) by double diffusion or with human serum. This antibody is reported to be suitable for use with free-floating, frozen, or paraffin embedded sections when used in immunohistochemistry. Variables assocated with assay conditions will dictate the proper working dilution.
      Biological Information
      Immunogenhighly purified, human erythrocyte SOD Cu/Zn.
      ImmunogenHuman
      HostSheep
      IsotypeIgG
      Species Reactivity
      • Human
      • Monkey
      • Mouse
      • Rat
      Antibody TypePolyclonal Antibody
      Concentration Label Please refer to vial label for lot-specific concentration
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Blue Ice Only
      Toxicity Standard Handling
      Storage -20°C
      Avoid freeze/thaw Avoid freeze/thaw
      Do not freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
      Canadian export regulations Due to the country and/or U.S. state of origin of the animal material used in this product, this product may not be exported to Canada.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      Anti-Superoxide Dismutase (Cu/Zn Enzyme) Sheep pAb SDS

      Title

      Safety Data Sheet (SDS) 

      Anti-Superoxide Dismutase (Cu/Zn Enzyme) Sheep pAb Certificates of Analysis

      TitleLot Number
      574597

      References

      Reference overview
      Pasinelli, P., et al. 1998. Proc. Natl. Acad. Sci. USA 95, 15763.

      Citations

      Title
    • Yu-Chin Lien, et al. (2006) Tumor necrosis factor receptor deficiency exacerbated Adriamycin-induced cardiomyocytes apoptosis: an insight into the Fas connection. Molecular Cancer Therapeutics 5, 261-269.
    • Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision16-August-2007 RFH
      SynonymsAnti-SOD
      ApplicationImmunoblotting (1:1000)
      Immunoelectrophoresis (see comments)
      Frozen sections (see comments)
      Paraffin sections (see comments)
      Free-floating sections (see comments)
      DescriptionSheep polyclonal antibody purified by DEAE ion-exchange chromatography. Recognizes the Cu/Zn superoxide dismutase protein.
      BackgroundSuperoxide dismutase Cu/Zn enzyme (SOD (Cu/Zn)) is a homodimeric metalloenzyme of aerobic organisms, comprised of subunits of ~16 kDa. Found in a variety of cell types, including erythrocytes, liver, and brain, it serves to protect cells against the oxidative damage of free radicals by catalyzing the conversion of superoxide anions (O2-) to molecular oxygen (O2) and hydrogen peroxide (H2O2).
      HostSheep
      Immunogen speciesHuman
      Immunogenhighly purified, human erythrocyte SOD Cu/Zn.
      IsotypeIgG
      Specieshuman, monkey, mouse, rat
      Positive controlHuman red blood cell lysate
      FormLiquid
      FormulationIn glycine-buffered saline, pH 7.4.
      Concentration Label Please refer to vial label for lot-specific concentration
      Preservative≤0.1% sodium azide
      CommentsThis antibody is monospecific as determined by immunoelectrophoresis against human red blood cell lysate and confirmed by immunodiffusion against a human red blood cell lysate and a known anti-SOD (Cu/Zn) antibody. Does not exhibit cross-reactivity with SOD (Mn) by double diffusion or with human serum. This antibody is reported to be suitable for use with free-floating, frozen, or paraffin embedded sections when used in immunohistochemistry. Variables assocated with assay conditions will dictate the proper working dilution.
      Storage -20°C
      Avoid freeze/thaw
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
      Toxicity Standard Handling
      ReferencesPasinelli, P., et al. 1998. Proc. Natl. Acad. Sci. USA 95, 15763.
      Citation
    • Yu-Chin Lien, et al. (2006) Tumor necrosis factor receptor deficiency exacerbated Adriamycin-induced cardiomyocytes apoptosis: an insight into the Fas connection. Molecular Cancer Therapeutics 5, 261-269.