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AB2202 Anti-PER2 Antibody

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100 µL  
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Replacement Information

Key Specifications Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
M, RWBRbSerumPolyclonal Antibody
Catalogue NumberAB2202
Trade Name
  • Chemicon
DescriptionAnti-PER2 Antibody
Background InformationPER2 is a component of the circadian clock mechanism which is essential for generating circadian rhythms. It is a negative element in the circadian transcriptional loop by Influencing clock function by interacting with other circadian regulatory proteins and transporting them to the nucleus. PER2 negatively regulates CLOCK NPAS2-BMAL1 BMAL2-induced transactivation. This gene is a member of the Period family of genes and is expressed in a circadian pattern in the suprachiasmatic nucleus, the primary circadian pacemaker in the mammalian brain. Genes in this family encode components of the circadian rhythms of locomotor activity, metabolism, and behavior. Circadian expression in the suprachiasmatic nucleus continues in constant darkness, and a shift in the light/dark cycle evokes a proportional shift of gene expression in the suprachiasmatic nucleus. The specific function of this gene is not yet known.
Product Information
  • C2C12 tissue lysate.
PresentationSerum with 0.05% NaN3
Quality LevelMQ100
ApplicationAnti-PER2 Antibody detects level of PER2 & has been published & validated for use in WB.
Key Applications
  • Western Blotting
Application NotesWestern Blot Analysis:
C2C12 lysate was resolved by electrophoresis, transferred to PVDF membrane and probed with anti-PER2 (1:500 dilution of this lot). Proteins were visualized using a Donkey anti-rabbit secondary antibody conjugated to HRP and a chemiluminescence detection system.
Biological Information
ImmunogenSynthetic peptide.
ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
SpecificityCat. # AB2202 will recognize the N-terminus of PER2.
Species Reactivity
  • Mouse
  • Rat
Species Reactivity NoteMouse and Rat. Reactivity with other species has not been determined.
Antibody TypePolyclonal Antibody
Entrez Gene Number
Gene Symbol
  • KIAA0347
  • hPER2
UniProt Number
Molecular WeightApprox. 136 kDa. Band may be observed at a much higher 200 kDa by the liver product depending on level of phophorylation and gel system used.
Physicochemical Information
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceRoutinely evaluated by western blot on C2C12 lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsMaintain at -20°C in undiluted aliquots for up to 1 year after date of receipt.
Packaging Information
Material Size100 µL
Transport Information
Supplemental Information
Global Trade Item Number
Catalog Number GTIN
AB2202 04053252273766


Anti-PER2 Antibody SDS


Safety Data Sheet (SDS) 

Anti-PER2 Antibody Certificates of Analysis

TitleLot Number
Anti-PER2 3059584
Anti-PER2 - 2153063 2153063
Anti-PER2 - 2370667 2370667
Anti-PER2 - 2462743 2462743
Anti-PER2 - 2022063 2022063
Anti-PER2 - 2064822 2064822
Anti-PER2 - 2228137 2228137
Anti-PER2 - 2262719 2262719
Anti-PER2 - 3218263 3218263
Anti-PER2 - 3282559 3282559


Reference overviewApplicationPub Med ID
Shell neurons of the master circadian clock coordinate the phase of tissue clocks throughout the brain and body.
Evans, JA; Suen, TC; Callif, BL; Mitchell, AS; Castanon-Cervantes, O; Baker, KM; Kloehn, I; Baba, K; Teubner, BJ; Ehlen, JC; Paul, KN; Bartness, TJ; Tosini, G; Leise, T; Davidson, AJ
BMC biology  13  43  2015

Show Abstract
26099272 26099272
Responses of brain and behavior to changing day-length in the diurnal grass rat (Arvicanthis niloticus).
Leach, G; Ramanathan, C; Langel, J; Yan, L
Neuroscience  234  31-9  2013

Show Abstract
Immunohistochemistry23313227 23313227
Antibodies for assessing circadian clock proteins in the rodent suprachiasmatic nucleus.
LeSauter, J; Lambert, CM; Robotham, MR; Model, Z; Silver, R; Weaver, DR
PloS one  7  e35938  2012

Show Abstract
22558277 22558277