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MABD24A4 Anti-NANOG Antibody, clone 7F7.1, Alexa Fluor® 488 conjugate

MABD24A4
100 µL  
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      Overview

      Replacement Information

      Key Specifications Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      HICCMAlexaFluor®488Monoclonal Antibody
      Description
      Catalogue NumberMABD24A4
      DescriptionAnti-NANOG Antibody, clone 7F7.1, Alexa Fluor® 488 conjugate
      Alternate Names
      • Homeobox protein NANOG
      • Homeobox transcription factor Nanog
      • hNanog
      Background InformationNANOG (Homeobox protein NANOG) is a member of the Nanog homeobox family of DNA-binding proteins. It is expressed in embryonic stem cells and confers pluripotency on these cells. Once embryonic stem cells become differentiated, NANOG expression is suppressed. NANOG is involved in the Hedgehog/Gli1 signaling pathway which has been implicated in the development and growth of various types of tumors. NANOG has also been identified as a key transcription factor used to generate induced pluripotent stem cells.
      References
      Product Information
      FormatAlexaFluor®488
      Control
      • H9 human embryonic stem cells.
      PresentationPurified mouse monoclonal IgG2a conjugated to Alexa Fluor® 488 in PBS with 0.1% sodium azide and 15mg/ml BSA.
      Quality LevelMQ100
      Applications
      ApplicationAnti-NANOG Antibody, clone 7F7.1, Alexa Fluor 488 conjugate.
      Key Applications
      • Immunocytochemistry
      Biological Information
      ImmunogenGST-tagged recombinant protein corresponding to human Nanog
      Clone7F7.1
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostMouse
      IsotypeIgG2a
      Species Reactivity
      • Human
      Antibody TypeMonoclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • NANOG
      Purification MethodProtein G Purified
      UniProt Number
      Molecular WeightThe uncojugated parent antibody (Catalog No. MABD24) has an observed MW of 39 kDA.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Immunocytochemistry in H9 human embryonic stem cells. Immunocytochemsitry Analysis: A 1:100 dilution of this antibody detected NANOG in H9 human embryonic stem cells.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsMaintain refrigerated at 2-8ºC protected from light in undiluted aliquots for up to 6 months from date of receipt.
      Packaging Information
      Material Size100 µL
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      Anti-NANOG Antibody, clone 7F7.1, Alexa Fluor® 488 conjugate SDS

      Title

      Safety Data Sheet (SDS) 

      Anti-NANOG Antibody, clone 7F7.1, Alexa Fluor® 488 conjugate Certificates of Analysis

      TitleLot Number
      Anti-NANOG, clone 7F7.1, Alexa -2795669 2795669
      Anti-NANOG, clone 7F7.1, Alexa Fluor#174; 488 conjugate - Q2044083 Q2044083
      Anti-NANOG, clone 7F7.1, Alexa Fluor® 488 conjugate 2450765
      Anti-NANOG, clone 7F7.1, Alexa Fluor® 488 conjugate 3139179
      Anti-NANOG, clone 7F7.1, Alexa Fluor® 488 conjugate - 2360027 2360027
      Anti-NANOG, clone 7F7.1, Alexa Fluor® 488 conjugate - 2382222 2382222
      Anti-NANOG, clone 7F7.1, Alexa Fluor® 488 conjugate - 3244012 3244012
      Anti-NANOG, clone 7F7.1, Alexa Fluor® 488 conjugate - 3386436 3386436
      Anti-NANOG, clone 7F7.1, Alexa Fluor® 488 conjugate - 3688994 3688994
      Anti-NANOG, clone 7F7.1, Alexa Fluor® 488 conjugate -2612578 2612578

      References

      Reference overviewPub Med ID
      X chromosome inactivation in human parthenogenetic embryonic stem cells following prolonged passaging.
      Qi, Q; Ding, C; Hong, P; Yang, G; Xie, Y; Wang, J; Huang, S; He, K; Zhou, C
      International journal of molecular medicine  35  569-78  2015

      Show Abstract
      25524499 25524499

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      Categories

      Life Science Research > Antibodies and Assays > Primary Antibodies