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ABF32 Anti-Fibroblast-specific Protein 1 (S100A4) Antibody

ABF32
100 µg  
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      Overview

      Replacement Information

      Key Specifications Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      H, M, R, B, Ca, EqWB, ICCRbAffinity PurifiedPolyclonal Antibody
      Description
      Catalogue NumberABF32
      DescriptionAnti-Fibroblast-specific Protein 1 (S100A4) Antibody
      Alternate Names
      • Protein S100-A4
      • Calvasculin
      • Metastasin
      • Placental calcium-binding protein
      • Protein Mts1
      • S100 calcium-binding protein A4
      Background InformationS100A4, also known as Fibroblast-specific Protein 1, is a member of the Ca2+- dependent S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 is a metastasis factor that may function in motility, invasion, and tubulin polymerization. Increased expression of S100A4 has been associated with various types of cancer.
      References
      Product Information
      FormatAffinity Purified
      Control
      • HeLa cell lysate
      PresentationPurified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationThis Anti-Fibroblast-specific Protein 1 (S100A4) Antibody is validated for use in WB, IC for the detection of Fibroblast-specific Protein 1 (S100A4).
      Key Applications
      • Western Blotting
      • Immunocytochemistry
      Application NotesImmunocytochemistry Analysis: A 1:500 dilution from a representative lot detected S100A4 in mouse neural stem cells.
      Biological Information
      ImmunogenKLH-conjugated linear peptide corresponding to the C-terminus of human S100A4.
      EpitopeC-terminus
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostRabbit
      SpecificityThis antibody recognizes S100A4 at the C-terminus.
      Species Reactivity
      • Human
      • Mouse
      • Rat
      • Bovine
      • Canine
      • Horse
      Species Reactivity NoteDemonstrated to react with Human, Mouse, and Rat.
      Predicted to react with Bovine, Canine, and Equine based on 100% sequence homology.
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Entrez Gene SummaryThe protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in motility, invasion, and tubulin polymerization. Chromosomal rearrangements and altered expression of this gene have been implicated in tumor metastasis. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008].
      Gene Symbol
      • S100A4
      • CAPL
      • MTS1
      Purification MethodAffinity Purfied
      UniProt Number
      UniProt SummarySUBUNIT STRUCTURE: Homodimer. Interacts with PPFIBP1 in a calcium-dependent mode.

      TISSUE SPECIFICITY: Ubiquitously expressed.

      SEQUENCE SIMILARITIES: Belongs to the S-100 family.

      Contains 2 EF-hand domains.
      Molecular Weight~12 kDa observed
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blot in HeLa cell lysate.

      Western Blot Analysis: 0.1 µg/mL of this antibody detected S100A4 in 10 µg of HeLa cell lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      Anti-Fibroblast-specific Protein 1 (S100A4) Antibody SDS

      Title

      Safety Data Sheet (SDS) 

      Anti-Fibroblast-specific Protein 1 (S100A4) Antibody Certificates of Analysis

      TitleLot Number
      Anti-Fibroblast-specific Protein 1 (S100A4) - 2147118 2147118
      Anti-Fibroblast-specific Protein 1 (S100A4) - 2049261 2049261
      Anti-Fibroblast-specific Protein 1 (S100A4) - 2246830 2246830
      Anti-Fibroblast-specific Protein 1 (S100A4) - 2297275 2297275
      Anti-Fibroblast-specific Protein 1 (S100A4) - 2327497 2327497
      Anti-Fibroblast-specific Protein 1 (S100A4) - 2363615 2363615
      Anti-Fibroblast-specific Protein 1 (S100A4) - 2490720 2490720
      Anti-Fibroblast-specific Protein 1 (S100A4) - 3231929 3231929
      Anti-Fibroblast-specific Protein 1 (S100A4) - 3270768 3270768
      Anti-Fibroblast-specific Protein 1 (S100A4) - 3499846 3499846

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      Product Families

      Categories

      Life Science Research > Antibodies and Assays > Primary Antibodies