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MAB2053 Anti-Disialoganglioside GD3 Antibody, clone MB3.6

MAB2053
100 µg  
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      Overview

      Replacement Information

      Key Specifications Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      HFC, IF, IHCMPurifiedMonoclonal Antibody
      Description
      Catalogue NumberMAB2053
      Brand Family Chemicon®
      Trade Name
      • Chemicon
      DescriptionAnti-Disialoganglioside GD3 Antibody, clone MB3.6
      References
      Product Information
      FormatPurified
      PresentationLiquid in 0.02M PB pH 7.6, 0.25M NaCl containing 0.1% NaN3.
      Quality LevelMQ100
      Applications
      ApplicationAnti-Disialoganglioside GD3 Antibody, clone MB3.6 is an antibody against Disialoganglioside GD3 for use in FC, IF, IH.
      Key Applications
      • Flow Cytometry
      • Immunofluorescence
      • Immunohistochemistry
      Application NotesImmunohistochemistry (frozen tissue sections)

      Immunofluorescence of cells in culture

      Flow cytometry: 1-2 μg per 10E6 cells

      Lysis of GD3 positive (melanoma) cells in presence of complement (Cheresh et al., 1985).

      Induction of antibody dependent cellular cyotoxicity (ADCC) {Ortaldo JR et al 1987 J Immunol 138(10):3566-3572.

      TLC analysis: Sjoberg, ER (1995) J. Biol. Chem. 270(7):2921-2930.{http://www.jbc.org/cgi/content/full/270/7/2921}





      Optimal working dilutions must be determined by end user.
      Biological Information
      ImmunogenFM9 melanoma cells
      CloneMB3.6
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostMouse
      SpecificityReacts specifically with human GD3 ganglioside (Cheresh et al., 1984). No cross-reactivity with other gangliosides purified from neuroblastoma or melanoma cells.
      IsotypeIgG3
      Species Reactivity
      • Human
      Antibody TypeMonoclonal Antibody
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsMaintain at 2-8°C in undiluted aliquots for up to 6 months.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      Anti-Disialoganglioside GD3 Antibody, clone MB3.6 SDS

      Title

      Safety Data Sheet (SDS) 

      Anti-Disialoganglioside GD3 Antibody, clone MB3.6 Certificates of Analysis

      TitleLot Number
      MOUSE ANTI-HUMAN DISIALOGANGLIOSIDE GD3 3075012
      MOUSE ANTI-HUMAN DISIALOGANGLIOSIDE GD3 - 2564847 2564847
      MOUSE ANTI-HUMAN DISIALOGANGLIOSIDE GD3 MONOCLONAL ANTIBODY - 2127790 2127790
      MOUSE ANTI-HUMAN DISIALOGANGLIOSIDE GD3 MONOCLONAL ANTIBODY - 2153567 2153567
      MOUSE ANTI-HUMAN DISIALOGANGLIOSIDE GD3 - 3272290 3272290
      MOUSE ANTI-HUMAN DISIALOGANGLIOSIDE GD3 - 3326737 3326737
      MOUSE ANTI-HUMAN DISIALOGANGLIOSIDE GD3 - 3447258 3447258
      MOUSE ANTI-HUMAN DISIALOGANGLIOSIDE GD3 - 3754816 3754816
      MOUSE ANTI-HUMAN DISIALOGANGLIOSIDE GD3 - 3810483 3810483
      MOUSE ANTI-HUMAN DISIALOGANGLIOSIDE GD3 -2594828 2594828