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ABN200 Anti-C-X-C chemokine receptor type 5 (CXCR5) Antibody

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ABN200
100 µg  
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Overview

Replacement Information

Key Specifications Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
H, MWB, IH(P)RbAffinity PurifiedPolyclonal Antibody
Description
Catalogue NumberABN200
DescriptionAnti-C-X-C chemokine receptor type 5 (CXCR5) Antibody
Alternate Names
  • C-X-C chemokine receptor type 5
  • CXC-R5
  • CXCR-5
  • Burkitt lymphoma receptor 1
  • Monocyte-derived receptor 15
  • MDR-15
  • CD185
Background InformationC-X-C chemokine receptor type 5 (CXCR5; Burkitt lymphoma receptor 1; Monocyte-derived receptor 15) is a G-protein coupled cytokine receptor that binds selectively to the CXCL13 (B lymphocyte chemoattractant) ligand, and mediates the development and function of the immune system. It is expressed in mature B cells, and facilitates the migration of B cells into follicles of the splenic white pulp, and enables deposition of antigen on follicular dendritic cells. It is also involved in the development of lymph nodes and Peyer’s patches. Previous studies have reported that the expression of CXCR5 increases in rheumatoid arthritis.
References
Product Information
FormatAffinity Purified
Control
  • SH-SY5Y cell lysate
PresentationPurified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality LevelMQ100
Applications
ApplicationAnti-C-X-C chemokine receptor type 5 (CXCR5) Antibody is an antibody against C-X-C chemokine receptor type 5 (CXCR5) for use in Western Blotting, IHC(P).
Key Applications
  • Western Blotting
  • Immunohistochemistry (Paraffin)
Application NotesImmunohistochemistry Analysis: A 1:1,000 dilution from representative lot detected C-X-C chemokine receptor type 5 (CXCR5) in mouse frontal cortex neurons and mouse spleen lymphocytes.
Biological Information
ImmunogenKLH-conjugated linear peptide corresponding to the cytoplasmic domain of human C-X-C chemokine receptor type 5 (CXCR5).
EpitopeCytoplasmic domain
ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
HostRabbit
SpecificityThis antibody recognizes the cytoplasmic domain of C-X-C chemokine receptor type 5 (CXCR5).
Species Reactivity
  • Human
  • Mouse
Antibody TypePolyclonal Antibody
Entrez Gene Number
Gene Symbol
  • CXCR5
  • BLR1
  • MDR15
Purification MethodAffinity Purfied
UniProt Number
Molecular Weight~51 / 38 kDa observed. Uniprot describes 2 isoforms produced by alternative splicing with molecular weights ~42 and ~37 kDa. The calculated molecular weight of this protein is 42 kDa, but can be observed at ~51 kDa due to high glycosylation.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blot in SH-SY5Y cell lysate.

Western Blot Analysis: 0.1 µg/mL of this antibody detected C-X-C chemokine receptor type 5 (CXCR5) in 10 µg of SH-SY5Y cell lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalog Number GTIN
ABN200 04053252696732

Documentation

Anti-C-X-C chemokine receptor type 5 (CXCR5) Antibody SDS

Title

Safety Data Sheet (SDS) 

Anti-C-X-C chemokine receptor type 5 (CXCR5) Antibody Certificates of Analysis

TitleLot Number
Anti-C-X-C chemokine receptor type 5 (CXCR5) - 2395797 2395797
Anti-C-X-C chemokine receptor type 5 (CXCR5) - 3482851 3482851
Anti-C-X-C chemokine receptor type 5 (CXCR5) - 3931721 3931721
Anti-C-X-C chemokine receptor type 5 (CXCR5) - Q2062044 Q2062044
Anti-C-X-C chemokine receptor type 5 (CXCR5) -2490075 2490075
Anti-C-X-C chemokine receptor type 5 (CXCR5) -2596513 2596513
Anti-C-X-C chemokine receptor type 5 (CXCR5) -2621118 2621118
Anti-C-X-C chemokine receptor type 5 (CXCR5) -2686116 2686116
Anti-C-X-C chemokine receptor type 5 (CXCR5) Polyclonal Antibody 3023606
Anti-C-X-C chemokine receptor type 5 -2793854 2793854