AB15708C3 Anti-Beta III Tubulin, Cy3 Conjugate Antibody

AB15708C3
100 µL  
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      Overview

      Replacement Information

      Key Specifications Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      H, M, R ICC Rb Cy3 Polyclonal Antibody
      Description
      Catalogue NumberAB15708C3
      DescriptionAnti-Beta III Tubulin, Cy3 Conjugate Antibody
      Background InformationTubulin is one of several members of a small family of globular proteins which polymerize to form cytoskeletal structures called microtubules. The most common members of the tubulin family are α-tubulin and β-tubulin. Tubulin dimers, typically composed of α- and β-tubulin subunits, assemble onto microtubules forming large polymers. β-III tubulin is a unique microtubule subunit that is found expressed almost exclusively in neurons. Due to the unique expression pattern of β-III tubulin it is often utilized as a marker to identify neuronal cells from other brain cells such as glia which do not express it. β-III tubulin also serves as a cytoarchitectural marker since it is primarily found within neurite extensions.
      References
      Product Information
      FormatCy3
      Control
      • Rat E18 cortex cells
      PresentationPurified rabbit polyclonal conjugated to Cy3 in PBS with 0.1% sodium azide and 15 mg/mL BSA.
      Quality LevelMQ100
      Applications
      ApplicationThis Anti-Beta III Tubulin, Cy3 Conjugate Antibody is validated for use in ICC for the detection of Beta III Tubulin.
      Key Applications
      • Immunocytochemistry
      Biological Information
      ImmunogenSynthetic linear peptide corresponding to human Beta III Tubulin.
      HostRabbit
      Species Reactivity
      • Human
      • Mouse
      • Rat
      Species Reactivity NoteDemonstrated to react with Rat. Predicted to react with Human and Mouse based on 100% sequence homology.
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • TUBB3
      • TUBB4
      • MC1R
      • beta-4
      Purification MethodAffinity Purfied
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: Q13509 # Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha-chain.
      SIZE: 450 amino acids; 50433 Da
      SUBUNIT: Dimer of alpha and beta chains.
      DOMAIN:SwissProt: Q13509 The highly acidic C-terminal region may bind cations such as calcium.
      SIMILARITY: Belongs to the tubulin family.
      Molecular Weight50 kDa calculated
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Immunocytochemistry in rat E18 cortex cells.
      Immunocytochemistry Analysis: A 1:100 dilution of this antibody detected Beta III Tubulin in rat E18 cortex cells.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µL
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      Anti-Beta III Tubulin, Cy3 Conjugate Antibody SDS

      Title

      Safety Data Sheet (SDS) 

      Anti-Beta III Tubulin, Cy3 Conjugate Antibody Certificates of Analysis

      TitleLot Number
      Anti-Beta III Tubulin, Cy3 Conjugate2981048
      Anti-Beta III Tubulin, Cy3 Conjugate2908618
      Anti-Beta III Tubulin, Cy3 Conjugate2849475
      Anti-Beta III Tubulin, Cy3 Conjugate3090568
      Anti-Beta III Tubulin, Cy3 Conjugate - 22972772297277
      Anti-Beta III Tubulin, Cy3 Conjugate - 25270662527066
      Anti-Beta III Tubulin, Cy3 Conjugate - 33101403310140
      Anti-Beta III Tubulin, Cy3 Conjugate - Q1972616Q1972616
      Anti-Beta III Tubulin, Cy3 Conjugate -26110502611050
      Anti-Beta III Tubulin, Cy3 Conjugate -26253612625361

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      Categories

      Life Science Research > Antibodies and Assays > Primary Antibodies