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MABT478 Anti-BCAR3 Antibody, clone 9D9.1

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MABT478
100 µg  
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Overview

Replacement Information

Key Specifications Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
HWBMPurifiedMonoclonal Antibody
Description
Catalogue NumberMABT478
DescriptionAnti-BCAR3 Antibody, clone 9D9.1
Alternate Names
  • Breast cancer anti-estrogen resistance protein 3
  • Novel SH2-containing protein 2
  • SH2 domain-containing protein 3B
Background InformationBreast cancer anti-estrogen resistance protein 3 (BCAR3), also known as Novel SH2-containing protein 2 (NSP2) and SH2 domain-containing protein 3B (SH2D3B) is an adapter protein that regulates the proliferation in breast cancer cells. BCAR3 may also be regulated by cellular adhesion to extracellular matrix proteins. BCAR3 is found in several cancer cell lines; however, it is not found in nonmalignant breast tissue. When BCAR3 is overexpressed, it confers anti-estrogen resistance in breast cancer cell lines.
References
Product Information
FormatPurified
PresentationPurified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality LevelMQ100
Applications
ApplicationAnti-BCAR3, clone 9D9.1 is an antibody against BCAR3 for use in Western Blotting.
Key Applications
  • Western Blotting
Biological Information
ImmunogenGST-tagged recombinant protein corresponding to human BCAR3.
Clone9D9.1
ConcentrationPlease refer to lot specific datasheet.
HostMouse
IsotypeIgG1κ
Species Reactivity
  • Human
Antibody TypeMonoclonal Antibody
Entrez Gene Number
Gene Symbol
  • BCAR3
  • NSP2
  • SH2D3B
  • UNQ271/PRO308
Purification MethodProtein G Purified
UniProt Number
Molecular Weight~93 kDa observed
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blotting in U2OS cell lysate.

Western Blotting Analysis: 0.5 µg/mL of this antibody detected BCAR3 in 10 µg of U2OS cell lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalog Number GTIN
MABT478 04055977115963