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AP1138 Anti-ARSA Mouse pAb

AP1138
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Overview

Replacement Information

Key Specifications Table

Species ReactivityHostAntibody Type
H M Polyclonal Antibody

Pricing & Availability

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AP1138-50UG
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      50 μg
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      Description
      OverviewRecognizes the ~55 kDa ARSA protein in human lymph node tissue.
      Catalogue NumberAP1138
      Brand Family Calbiochem®
      Application Data
      Detection of human ARSA by immunoblotting. Sample: Whole cell lysate from 293T cells transfected with human ARSA (lane 1) non-transfected 293T cells (lane 2). Primary antibody: Anti-ARSA Mouse pAb (Cat. No. AP1138) (1-5 µg/ml). Detection: chemiluminescence.

      Detection of human ARSA by staining paraffin sections. Sample: Formalin/PFA-fixed, paraffin-embedded human lymph node tissue. Primary antibody: Anti-ARSA Mouse pAb (Cat. No. AP1138) (3 µg/ml). Detection: colrimetric (DAB).
      References
      Product Information
      FormLiquid
      FormulationIn PBS, pH 7.2.
      Positive controlHuman lymph node tissue
      PreservativeNone
      Quality LevelMQ100
      Applications
      Key Applications Immunoblotting (Western Blotting)
      Paraffin Sections
      Application NotesImmunoblotting (1-5 µg/ml)
      Paraffin Sections (3 µg/ml)
      Application CommentsVariables associated with assay conditions will dictate the proper working dilution.
      Biological Information
      ImmunogenFull length human ARSA (aa 1-507)
      ImmunogenHuman
      HostMouse
      IsotypeIgG
      Species Reactivity
      • Human
      Antibody TypePolyclonal Antibody
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Blue Ice Only
      Toxicity Regulatory Review
      Storage -20°C
      Avoid freeze/thaw Avoid freeze/thaw
      Do not freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      Anti-ARSA Mouse pAb SDS

      Title

      Safety Data Sheet (SDS) 

      Anti-ARSA Mouse pAb Certificates of Analysis

      TitleLot Number
      AP1138
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision20-October-2010 JLN
      ApplicationImmunoblotting (1-5 µg/ml)
      Paraffin Sections (3 µg/ml)
      Application Data
      Detection of human ARSA by immunoblotting. Sample: Whole cell lysate from 293T cells transfected with human ARSA (lane 1) non-transfected 293T cells (lane 2). Primary antibody: Anti-ARSA Mouse pAb (Cat. No. AP1138) (1-5 µg/ml). Detection: chemiluminescence.

      Detection of human ARSA by staining paraffin sections. Sample: Formalin/PFA-fixed, paraffin-embedded human lymph node tissue. Primary antibody: Anti-ARSA Mouse pAb (Cat. No. AP1138) (3 µg/ml). Detection: colrimetric (DAB).
      DescriptionPurified mouse polyclonal antibody. Recognizes the ~55 kDa ARSA protein.
      BackgroundARSA hydrolyzes cerebroside sulfate. Defects in ARSA are known to cause metachromatic leukodystrophy (MLD). MLD is a disease due to a lysosomal storage defect. It is characterized by intralysosomal storage of cerebroside-3-sulfate in neural and non-neural tissues, with a diffuse loss of myelin in the central nervous system. Progressive demyelination causes a variety of neurological symptoms, including gait disturbances, ataxias, optical atrophy, dementia, seizures, and spastic tetraparesis. Three forms of the disease can be distinguished according to the age at onset: late-infantile, juvenile and adult.
      HostMouse
      Immunogen speciesHuman
      ImmunogenFull length human ARSA (aa 1-507)
      IsotypeIgG
      Specieshuman
      Positive controlHuman lymph node tissue
      FormLiquid
      FormulationIn PBS, pH 7.2.
      PreservativeNone
      CommentsVariables associated with assay conditions will dictate the proper working dilution.
      Storage -20°C
      Avoid freeze/thaw
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
      Toxicity Regulatory Review