505821 AF-DX 116 - CAS 102394-31-0 - Calbiochem

505821
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Overview

Replacement Information

Key Specifications Table

Empirical FormulaCAS #
C₂₄H₃₁N₅O₂ 102394-31-0

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      Glass bottle 10 mg
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      Description
      OverviewSelective presynaptic muscarinic receptor M2 antagonist with cardioselectivity. Exhibits antiarrhythmic effects in vivo, also shown to reverse the memory impairment effect of insulin in a mouse model.
      Catalogue Number505821
      Brand Family Calbiochem®
      SynonymsMuscarinic Receptor (mAChR) M2 antagonist, AF-DX 116, Otenzepad, AF-DX116, AF-DX-116, AFDX116
      References
      ReferencesLanzafame A., et al. 2001. Eur J Pharmacol. 416, 235.
      Kopf S., et al. 1998. Neurobiol Learn Mem. 70, 305.
      Naito, H., et al. 1997. Heart Vessels. 12, 229.
      Hammer, R., et al. 1986. Life Sci. 38, 1653.
      Product Information
      CAS number102394-31-0
      FormWhite solid
      Hill FormulaC₂₄H₃₁N₅O₂
      Chemical formulaC₂₄H₃₁N₅O₂
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetM₂
      Purity≥99% by HPLC
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      R PhraseR: 22

      Harmful if swallowed.
      S PhraseS: 46

      If swallowed, seek medical advice immediately and show this container or label.
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
      Toxicity Harmful
      Storage +2°C to +8°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      AF-DX 116 - CAS 102394-31-0 - Calbiochem SDS

      Title

      Safety Data Sheet (SDS) 

      References

      Reference overview
      Lanzafame A., et al. 2001. Eur J Pharmacol. 416, 235.
      Kopf S., et al. 1998. Neurobiol Learn Mem. 70, 305.
      Naito, H., et al. 1997. Heart Vessels. 12, 229.
      Hammer, R., et al. 1986. Life Sci. 38, 1653.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision20-September-2013 JSW
      SynonymsMuscarinic Receptor (mAChR) M2 antagonist, AF-DX 116, Otenzepad, AF-DX116, AF-DX-116, AFDX116
      DescriptionSelective presynaptic muscarinic receptor M2 antagonist with cardioselectivity. Exhibits antiarrhythmic effects in vivo, also shown to reverse the memory impairment effect of insulin in a mouse model.
      FormWhite solid
      CAS number102394-31-0
      Chemical formulaC₂₄H₃₁N₅O₂
      Structure formulaStructure formula
      Purity≥99% by HPLC
      SolubilityDMSO
      Storage +2°C to +8°C
      Protect from light
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Toxicity Harmful
      ReferencesLanzafame A., et al. 2001. Eur J Pharmacol. 416, 235.
      Kopf S., et al. 1998. Neurobiol Learn Mem. 70, 305.
      Naito, H., et al. 1997. Heart Vessels. 12, 229.
      Hammer, R., et al. 1986. Life Sci. 38, 1653.