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575003 α-Synuclein A53T, Human, Recombinant, E. coli

575003
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575003-200UG
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      Plastic ampoule 200 μg
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      575003-UG
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          Description
          OverviewRecombinant, human α-synuclein containing an A53T mutation and expressed in E. coli. A point mutant (A53T) of α-synuclein gene that has been linked to autosomal dominant early-onset Parkinson’s disease (PD).
          Catalogue Number575003
          Brand Family Calbiochem®
          References
          ReferencesLashuel, H.A., et al. 2002. J. Mol. Biol. 322, 1089.
          Park, S.M., et al. 2002. Blood 100, 2506.
          Polymeropoulos, M.H., et al. 1997. Science 276, 2045.
          Product Information
          FormLiquid
          FormulationIn 100 mM NaCl, 20 mM Tris-HCl, pH 7.5.
          Quality LevelMQ100
          Applications
          Biological Information
          Purity≥95% by SDS-PAGE
          Concentration Label Please refer to vial label for lot-specific concentration
          Physicochemical Information
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Dry Ice Only
          Toxicity Standard Handling
          Storage -20°C
          Avoid freeze/thaw Avoid freeze/thaw
          Do not freeze Ok to freeze
          Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          α-Synuclein A53T, Human, Recombinant, E. coli SDS

          Title

          Safety Data Sheet (SDS) 

          α-Synuclein A53T, Human, Recombinant, E. coli Certificates of Analysis

          TitleLot Number
          575003

          References

          Reference overview
          Lashuel, H.A., et al. 2002. J. Mol. Biol. 322, 1089.
          Park, S.M., et al. 2002. Blood 100, 2506.
          Polymeropoulos, M.H., et al. 1997. Science 276, 2045.
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision12-September-2008 RFH
          DescriptionRecombinant, human α-synuclein containing an A53T mutation and expressed in E. coli. α-synuclein is an acidic neuronal protein of 140 amino acids that has been implicated in the pathogenesis of Parkinson's disease and related neurodegenerative disorders. α-Synuclein (A53T) is a point mutant of the α-synuclein gene that has been linked to autosomal dominant early onset Parkinson's Disease (PD). The apparent molecular weight on SDS-PAGE is ~19-20 kDa.
          FormLiquid
          FormulationIn 100 mM NaCl, 20 mM Tris-HCl, pH 7.5.
          Concentration Label Please refer to vial label for lot-specific concentration
          Purity≥95% by SDS-PAGE
          Storage -20°C
          Avoid freeze/thaw
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
          Toxicity Standard Handling
          ReferencesLashuel, H.A., et al. 2002. J. Mol. Biol. 322, 1089.
          Park, S.M., et al. 2002. Blood 100, 2506.
          Polymeropoulos, M.H., et al. 1997. Science 276, 2045.