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Purospher® HPLC columns are based upon a high-purity silica for excellent separations with very good peak symmetry. The base material for Purospher® high-purity HPLC columns consists of tetra-alkoxysilane. Due to the absence of heavy metals in the silica matrix and in combination with a complete coverage of the silica surface, this stationary phase enables tailing-free chromatography of acidic, basic and chelating compounds. This is of particular advantage for method development.

© Merck KGaA, Darmstadt, Germany, 2013

All references to Merck refer to Merck KGaA, Darmstadt, Germany.


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