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26 May 2012
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An oxaquinolizidine alkaloid isolated from a marine sponge. A very potent, reversible, and membrane-permeable blocker of IP3-mediated Ca2+ release (IC50 = 358 nM) that does not interact with the IP3-binding site. Displays high selectivity over the skeletal isoform of the ryanodine receptor type 1 (RyR-1). Also blocks bradykinin- and carbamylcholine-induced Ca2+ efflux from the endoplasmic reticulum stores in a reversible manner.
| Alternatives | |
|---|---|
| 682162 | Xestospongin D, Xestospongia sp. |
| Alternative products for Xestospongin C, Xestospongia sp. | |
| 682162 | Xestospongin D, Xestospongia sp. |
| Accessories for Xestospongin C, Xestospongia sp. |
| Product information | |||
|---|---|---|---|
| Form | White solid | ||
| Molar mass | 446.7 | ||
| Protect from Light | Yes | ||
| Packaged under inert gas | Yes | ||
| Purity | ≥90% by TLC | ||
| Solubility | DMSO, EtOH, or MeOH | ||
| Chemical formula | C28H50N2O2 | ||
| Store and ship information | |||
|---|---|---|---|
| Storage | -20°C | ||
| Ship |
Ambient Temperature Only
Harmful |
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| Safety information | |||
|---|---|---|---|
| S Phrase |
S: 22-24/25-36/37/39-45 Do not breathe dust. Avoid contact with skin and eyes. Wear suitable protective clothing, gloves and eye/face protection. In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible). |
||
| R Phrase |
R: 20/21/22 Harmful by inhalation, in contact with skin and if swallowed. |
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