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612400  Tissue Transglutaminase, His•Tag®, Human, Recombinant, S. frugiperda

rh-tTG, TGase

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26 May 2012

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Full-length, recombinant, human tissue transglutaminase fused to a HisTag® sequence and expressed in s. frugiperda insect cells. Suitable as a control for ELISA or Western blots. Tissue transglutaminase is a calcium-activated enzyme, which forms cross-links between glutamine and lysine side-chains of polypeptides. TGase-mediated protein crosslinking has been implicated in a variety of natural processes ranging from the stabilization of fibrin clots to production of the epidermal cell envelope and the fluid barrier of the skin. TGases are also involved in both function and dysfunction of the central and peripheral nervous systems. More recently, TGases have been implicated in the onset of Huntington’s Disease (HD) as well as Celiac Disease (CD). Suitable for use as a standard in ELISA or immunoblots.
Product information
Form Liquid
Formulation In 20 mM Tris-HCl, 1 mM EDTA, 20% glycerol, pH 8.1-8.5.
Molar mass 85000
Avoid freeze/thaw Yes
Purity ≥90% by SDS-PAGE
Store and ship information
Storage -20°C
Ship Dry Ice Only
Standard Handling

© Merck KGaA, Darmstadt, Germany, 2012

All references to Merck refer to Merck KGaA, Darmstadt, Germany.


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