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26 May 2012
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A cell-permeable naphthyridinyl-phenolic compound that selectively enhances cytokine-induced STAT1 transcription activity, but not that of STAT3 or NF-κB. Shown to prolong INF-γ-induced tyrosine phosphorylation of STAT1 in NIH3T3 cells and accentuate the STAT1-dependent growth inhibition in MCF-7 and 2fTGH cancer cells.
| Product information | |||
|---|---|---|---|
| Form | Orange solid | ||
| Molar mass | 222.2 | ||
| Protect from Light | Yes | ||
| Packaged under inert gas | Yes | ||
| Purity | ≥98% by HPLC | ||
| Solubility | DMSO | ||
| Chemical formula | C14H10N2O | ||
| CAS number | 65182-56-1 | ||
| Store and ship information | |||
|---|---|---|---|
| Storage | +2°C to +8°C | ||
| Ship |
Ambient Temperature Only
Regulatory Review |
||
