555551
Rho Kinase Inhibitor II
N-(4-Pyridyl)-N′-(2,4,6-trichlorophenyl)urea
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EMD Millipore
290 Concord Road
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United States
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26 May 2012
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A pyridyl urea compound that acts as a potent, selective, reversible, and ATP-competitive inhibitor of Rho-associated protein kinase (ROCK; IC50 = 0.2 µM). Displays little activity towards Erk, PKA, PKC, PDGFR, or c-Kit/SCFR (IC50 > 10 µM).
| Product information | |||
|---|---|---|---|
| Form | White solid | ||
| Primary Target | ROCK | ||
| Primary Target IC50 | 0.2 µM | ||
| Molar mass | 316.6 | ||
| Protect from Light | Yes | ||
| Packaged under inert gas | Yes | ||
| ATP Competitive | Yes | ||
| Purity | ≥95% by HPLC | ||
| Solubility | DMSO | ||
| Chemical formula | C12H8Cl3N3O | ||
| CAS number | 97627-27-5 | ||
| Store and ship information | |||
|---|---|---|---|
| Storage | +2°C to +8°C | ||
| Ship |
Ambient Temperature Only
Standard Handling |
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