530050
PRIMA-1
2,2-Bis(hydroxymethyl)-1-azabicyclo[2,2,2]octan-3-one, p53 Reactivation and Induction of Massive Apoptosis
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25 May 2013
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A cell-permeable quinuclidinone analog with antitumor properties. Restores biochemical and biological function to mutant p53 and induces p53-dependent apoptosis in vitro and in vivo. Induces apoptosis in breast cancer cells expressing mutant p53.
| Product information | |||
|---|---|---|---|
| Form | Off-white solid | ||
| Molar mass | 185.2 | ||
| Hygrocopic | Yes | ||
| Packaged under inert gas | Yes | ||
| Purity | ≥95% by NMR | ||
| Solubility | H2O | ||
| Chemical formula | C9H15NO3 | ||
| CAS number | 5608-24-2 | ||
| Store and ship information | |||
|---|---|---|---|
| Storage | +2°C to +8°C | ||
| Ship |
Ambient Temperature Only
Standard Handling |
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