Phosphodiesterase 4D5, Active, Human, Recombinant, S. frugiperda
cAMP-specific phosphodiesterase 4D isoform 5, PDE4D5
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290 Concord Road
01821 Billerica, MA
Phone: 781 533-6000
23 May 2013
This product has been discontinued.
Full-length, recombinant, human phosphodiesterdase 4D5 (PDE4D5) expressed in S. frugiperda insect cells using a baculovirus expression system. PDE4D5 is expressed primarily in cardiac and vascular myocytes where it is found preferentially sequestered to β-arrestin. Supplied as a partially purified preparation of catalytically active enzyme useful for inhibitor and activator assays.
|Formulation||150 mM NaCl, 10 mM Tris, 0.1% NP-40, pH 8.3|
|Unit definition||One unit is defined as the amount of enzyme that is required to convert 1 pmol cAMP to AMP per min at pH 7.5 at 30°C.|
|Activity||≥ 0.5 U/µl|
|Store and ship information|
Dry Ice Only
Increasing concentration of PDE inhibitor, rolipram, was added to enzyme and the activity assayed.