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EMD Millipore
290 Concord Road
01821 Billerica, MA
United States
Phone: 781 533-6000
Fax: +49 6151 72 2000
E-mail: Customer.CareDesk@emdchemicals.com
25 May 2012
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Recombinant, human platelet-derived growth factor (disulfide-linked dimer of two 109 amino acid B-chain monomers) expressed in E. coli. Shown to be a potent chemoattractant for neutrophils, mesenchymal and mononuclear cells. Has the same amino acid sequence as mature human PDGF-B. Rapidly activates protein kinase D in vascular smooth muscle cells.
| Product information | |||
|---|---|---|---|
| Form | Lyophilized | ||
| Formulation | Lyophilized from a sterile-filtered solution, carrier free. | ||
| Molar mass | 25000 | ||
| Biological activity | ED50 = 1-5 ng/ml as determined by the dose dependent proliferation of BALB/c 3T3 cells | ||
| Purity | ≥95% by SDS-PAGE | ||
| Contaminants | Endotoxin: ≤1 ng/µg PDGF-BB | ||
| Solubility | 100 mM acetic acid, 0.1% BSA | ||
| Merck USA index | 14, 7525 | ||
| Store and ship information | |||
|---|---|---|---|
| Storage | ≤ -70°C | ||
| Ship |
Ambient Temperature Only
Standard Handling |
||
