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506600  Pamidronate, Disodium Salt

3-Amino-1-hydroxypropylidene-bisphosphonic Acid, 2Na, Pentahydrate

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25 May 2012

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506600-10MG  10 mg 
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A potent and specific inhibitor of bone resorption that does not cause any significant detrimental effect on bone growth and mineralization at concentrations used. Effective in a variety of conditions characterized by pathologically enhanced bone turnover, including Paget’s disease, hypercalcaemia of malignancy, osteolytic bone metastasis, steroid-induced osteoporosis, and idiopathic osteoporosis. Inhibits breast cancer cell growth by inducing cell death in vitro. Provided in hydrated form, contains five molecules of water.
Product information
Form White solid
Molar mass 369.1
Hygrocopic Yes
Purity ≥98% by HPLC
Solubility H2O
Chemical formula C3H9NO7P2·2Na·5H2O
RTECS SZ6522666
CAS number 109552-15-0
Merck USA index 14, 7003
Store and ship information
Storage -20°C
Ship Ambient Temperature Only
Harmful & Carcinogenic / Teratogenic
Safety information
S Phrase S: 36-45

Wear suitable protective clothing.
In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
R Phrase R: 20/21/22-61

Harmful by inhalation, in contact with skin and if swallowed.
May cause harm to the unborn child.
Pamidronate, Disodium Salt, molecular structure

© Merck KGaA, Darmstadt, Germany, 2012

All references to Merck refer to Merck KGaA, Darmstadt, Germany.


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