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492030  NS 2028

4H-8-Bromo-1,2,4-oxadiazolo(3,4-d)benz(b)(1,4)oxazin-1-one

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25 May 2012

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492030-5MG  5 mg 
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Prices are subject to change without notice.
Potent, specific, and irreversible inhibitor of soluble guanylyl cyclase (IC50 = 30 nM for basal and 200 nM for NO-stimulated enzyme activity; IC50 = 17 nM for S-nitrosoglutathione-enhanced soluble guanylyl cyclase activity in homogenates of mouse cerebellum).
Product information
Form White to off-white solid
Primary Target basal soluble guanylyl cyclase
Primary Target IC50 30 nM
Secondary target 200 nM for NO-stimulated enzyme activity; IC50 = 17 nM for S-nitrosoglutathione-enhanced soluble guanylyl cyclase activity in homogenates of mouse cerebellum
Molar mass 269.0
Protect from Moisture Yes
Purity ≥98% by NMR
Solubility DMSO, EtOH, or CHCl3
Chemical formula C9H5BrN2O3
CAS number 204326-43-2
Store and ship information
Storage +2°C to +8°C
Ship Ambient Temperature Only
Standard Handling
NS 2028, molecular structure

© Merck KGaA, Darmstadt, Germany, 2012

All references to Merck refer to Merck KGaA, Darmstadt, Germany.


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