475913
Mycophenolic Acid
6-(4-Hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexenoic Acid, MPA
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EMD Millipore
290 Concord Road
01821 Billerica, MA
United States
Phone: 781 533-6000
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E-mail: Customer.CareDesk@emdchemicals.com
25 May 2012
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An immunosuppressive agent that inhibits de novo purine nucleotide synthesis via inhibition of inosine monophosphate dehydrogenase and prevents the formation of XMP and GMP. Useful for selection of animal cells that express the E. coli gene coding for xanthine-guanine phosphoribosyltransferase. Also suppresses cytokine-induced nitric oxide production in mouse and rat vascular endothelial cells.
| Product information | |||
|---|---|---|---|
| Form | White to off-white solid | ||
| Molar mass | 320.4 | ||
| Purity | ≥95% by HPLC | ||
| Solubility | EtOH or 0.1 N NaOH | ||
| Chemical formula | C17H20O6 | ||
| RTECS | MP8050000 | ||
| CAS number | 24280-93-1 | ||
| Merck USA index | 14 6327 | ||
| Store and ship information | |||
|---|---|---|---|
| Storage | +15°C to +30°C | ||
| Ship |
Ambient Temperature Only
Harmful & Carcinogenic / Teratogenic |
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| Safety information | |||
|---|---|---|---|
| S Phrase |
S: 22-36 Do not breathe dust. Wear suitable protective clothing. |
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| R Phrase |
R: 20/21/22-40 Harmful by inhalation, in contact with skin and if swallowed. Limited evidence of a carcinogenic effect. |
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