For general questions please contact our Customer Service:
EMD Millipore
290 Concord Road
01821 Billerica, MA
United States
Phone: 781 533-6000
Fax: +49 6151 72 2000
E-mail: Customer.CareDesk@emdchemicals.com
25 May 2012
loading
A 26-residue polypeptide from bee venom that binds calmodulin in a Ca2+-dependent manner. A stimulator of Giα and G11α activity that is reported to inhibit adenylate cyclase activity in synaptic membranes. Activates phospholipase A2 and inhibits protein kinase C (IC50 = 5-7 µM) by binding to the catalytic domain in a Mg2+-ATP sensitive manner. Has also been used for affinity purification of several Ca2+-binding proteins.
| Product information | |||
|---|---|---|---|
| Peptide Sequence | H-Gly-Ile-Gly-Ala-Val-Leu-Lys-Val-Leu-Thr-Thr-Gly-Leu-Pro-Ala-Leu-Ile-Ser-Trp-Ile-Lys-Arg-Lys-Arg-Gln-Gln-NH2 | ||
| Form | Lyophilized | ||
| Primary Target | PKC | ||
| Primary Target IC50 | 5-7 µM | ||
| Molar mass | 2846.5 | ||
| Purity | >97% by HPLC | ||
| Sold on the basis of peptide content | Yes | ||
| Solubility | H2O | ||
| Chemical formula | C131H229N39O31 | ||
| RTECS | OS3960000 | ||
| CAS number | 37231-28-0 | ||
| Merck USA index | 14, 5824 | ||
| Store and ship information | |||
|---|---|---|---|
| Storage | -20°C | ||
| Ship |
Ambient Temperature Only
Standard Handling |
||
