420600
Ketoconazole
cis-1-Acetyl-4-[4-[[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]piperazine, R-41400
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EMD Millipore
290 Concord Road
01821 Billerica, MA
United States
Phone: 781 533-6000
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E-mail: Customer.CareDesk@emdchemicals.com
25 May 2012
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An inhibitor of cytochrome P-450 in steroid biosynthesis. An antifungal agent that displays potent anti-metastatic, anti-neoplastic, and anti-psoriatic activities. Also acts as an inhibitor of 5-lipoxygenase (5-LO; IC50 = 26 µM) and thromboxane synthase activities.
| Product information | |||
|---|---|---|---|
| Form | Off-white solid | ||
| Primary Target | 5-LO | ||
| Primary Target IC50 | 26 µM | ||
| Molar mass | 531.4 | ||
| Purity | ≥98% by HPLC | ||
| Solubility | DMSO | ||
| Chemical formula | C26H28Cl2N4O4 | ||
| RTECS | TK7912300 | ||
| CAS number | 65277-42-1 | ||
| Merck USA index | 14, 5302 | ||
| Store and ship information | |||
|---|---|---|---|
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Hazardous Materials Attention: Due to the nature of the Hazardous Materials in this shipment, additional shipping chargesmay be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges. |
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| Storage | +2°C to +8°C | ||
| Ship |
Ambient Temperature Only
Toxic & Carcinogenic / Teratogenic |
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| Safety information | |||
|---|---|---|---|
| S Phrase |
S: 22-26-36 Do not breathe dust. In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing. |
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| R Phrase |
R: 25-40-63-36/37/38 Toxic if swallowed. Limited evidence of a carcinogenic effect. Possible risk of harm to the unborn child. Irritating to eyes, respiratory system and skin. |
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