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407950  Ionomycin, Free Acid, Streptomyces conglobatus

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25 May 2012

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407950-10MG  10 mg 
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407950-1MG  1 mg 
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407950-5MG  5 mg 
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Prices are subject to change without notice.
Highly specific for divalent cations and more effective than A23187 (Cat. No. 100105) as a mobile ion carrier for Ca2+. Complexes with Ca2+ between pH 7 and 9.5. In contrast to A23187, it is not fluorescent. Useful for studies of Ca2+ transport across biological membranes and measurement of cytoplasmic free Ca2+. Induces apoptotic neuronal degeneration in embryonic cortical neurons and cell cycle arrest in the G1 phase in mature Burkitt lymphoma cell lines. Absorption max. (280 nm, MeOH): 18,600 M-1cm-1.
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Product information
Form Waxy solid
Molar mass 709.0
Protect from Light Yes
Packaged under inert gas Yes
Purity ≥90% by HPLC
Solubility DMSO or MeOH
Chemical formula C41H72O9
RTECS NO0600000
CAS number 56092-81-0
Store and ship information
Storage +2°C to +8°C
Ship Ambient Temperature Only
Harmful
Safety information
S Phrase S: 36

Wear suitable protective clothing.
R Phrase R: 22

Harmful if swallowed.
Ionomycin, Free Acid, <i>Streptomyces conglobatus</i>, molecular structure

© Merck KGaA, Darmstadt, Germany, 2012

All references to Merck refer to Merck KGaA, Darmstadt, Germany.


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