Interleukin-3, Human, Recombinant, E. coli
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19 May 2013
This product has been discontinued.
Recombinant, human interleukin-3 expressed in E. coli. Stimulates the production and differentiation of macrophages, neutrophils, basophils, mast cells, and eosinophils. As a hematopoietic colony-stimulating factor, IL-3 interacts with very early multipotent hematopoietic progenitor cells. IL-3 supports colony formation in soft agar of bone marrow cells of the granulocyte, macrophage, megakaryocyte, and erythrocyte lineages. IL-3 is reported to suppress the secretion of IL-12 and shift dendritic cells from the Th1 to Th2 phenotype.
|Biological activity||ED50= 100-250 pg/ml as measured in a cell proliferation assay with a human, IL-3 -dependent cell line.|
|Purity||≥95% by SDS-PAGE|
|Contaminants||Endotoxin: ≤100 pg/μg IL-3|
|Merck USA index||14, 4995|
|Store and ship information|
Ambient Temperature Only