407601
Interleukin-1 Receptor-Associated-Kinase-1/4 Inhibitor
N-(2-Morpholinylethyl)-2-(3-nitrobenzoylamido)-benzimidazole, IRAK-1/4 Inhibitor
For general questions please contact our Customer Service:
EMD Millipore
290 Concord Road
01821 Billerica, MA
United States
Phone: 781 533-6000
Fax: +49 6151 72 2000
E-mail: Customer.CareDesk@emdchemicals.com
25 May 2012
loading
A cell-permeable benzimidazole compound that acts as a potent and selective inhibitor of interleukin-1 receptor-associated kinases (IC50 = 300 nM and 200 nM for IRAK-1 and -4). Shown to exhibit little activity against a panel of 27 other kinases (IC50 >10 µM), including lck and src.
| Product information | |||
|---|---|---|---|
| Form | Yellow crystalline solid | ||
| Molar mass | 395.4 | ||
| Protect from Light | Yes | ||
| Packaged under inert gas | Yes | ||
| Purity | ≥95% by HPLC | ||
| Solubility | DMSO | ||
| Chemical formula | C20H21N5O4 | ||
| CAS number | 509093-47-4 | ||
| Store and ship information | |||
|---|---|---|---|
| Storage | -20°C | ||
| Ship |
Ambient Temperature Only
Harmful |
||
| Safety information | |||
|---|---|---|---|
| S Phrase |
S: 36 Wear suitable protective clothing. |
||
| R Phrase |
R: 20/21/22 Harmful by inhalation, in contact with skin and if swallowed. |
||
