For general questions please contact our Customer Service:
EMD Millipore
290 Concord Road
01821 Billerica, MA
United States
Phone: 781 533-6000
Fax: 800-645-5439
E-mail: Customer.CareDesk@emdchemicals.com
23 May 2013
loading
A highly potent cell-permeable and reversible inhibitor of glycogen synthase kinase-3β (GSK-3β; IC50 = 9 nM). Also inhibits Cdk1 (IC50 = 25 nM) and Cdk5 (IC50 = 20 nM) activities. Acts by binding to the ATP-binding pocket of these enzymes.
| Product information | |||
|---|---|---|---|
| Form | Dark red solid | ||
| Primary Target | Gsk-3β | ||
| Primary Target IC50 | 9 nM | ||
| Secondary target | Cdk1(IC50 = 25 nM), Cdks (IC50 = 20 nM) | ||
| Molar mass | 403.2 | ||
| Protect from Light | Yes | ||
| Packaged under inert gas | Yes | ||
| Purity | ≥97% by HPLC | ||
| Solubility | DMSO | ||
| Chemical formula | C16H10IN3O2 | ||
| CAS number | 331467-03-9 | ||
| Store and ship information | |||
|---|---|---|---|
| Storage | -20°C | ||
| Ship |
Ambient Temperature Only
Standard Handling |
||
