361547
GSK-3β Inhibitor VI
2-Chloro-1-(4,5-dibromo-thiophen-2-yl)-ethanone
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EMD Millipore
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01821 Billerica, MA
United States
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25 May 2012
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A thienyl α-chloromethyl ketone compound that acts as a cell-permeable, irreversible, and non-ATP competitive inhibitor of GSK-3β (IC50 = 1 µM). This reactive alkylating agent is selective towards GSK-3β and does not affect PKA activity even at concentrations as high as 100 µM.
| Product information | |||
|---|---|---|---|
| Form | Orange solid | ||
| Primary Target | Gsk-3β | ||
| Primary Target IC50 | 1 µM | ||
| Molar mass | 318.4 | ||
| Protect from Light | Yes | ||
| Packaged under inert gas | Yes | ||
| Cell permeable | Yes | ||
| Reversible | Yes | ||
| Purity | ≥90% by HPLC | ||
| Solubility | DMSO or EtOH | ||
| Chemical formula | C6H3Br2ClOS | ||
| CAS number | 62673-69-2 | ||
| Store and ship information | |||
|---|---|---|---|
| Storage | -20°C | ||
| Ship |
Shipped with Blue Ice or with Dry Ice
Standard Handling |
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