364200
GM 1489
N-[(2R)-2-(Carboxymethyl)-4-methylpentanoyl]-L-tryptophan-(S)-methyl-benzylamide
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EMD Millipore
290 Concord Road
01821 Billerica, MA
United States
Phone: 781 533-6000
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E-mail: Customer.CareDesk@emdchemicals.com
25 May 2012
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A potent broad-range inhibitor of matrix metalloproteinases (MMPs). Inhibits MMPs in vitro (Ki = 0.2 nM for MMP-1; Ki = 500 nM for MMP-2; Ki = 20 µM for MMP-3; Ki = 100 nM for MMP-8; and Ki = 100 nM for MMP-9). Also reduces the inflammatory and the hyperproliferative responses that occur following topical phorbol ester application.
| Product information | |||
|---|---|---|---|
| Form | Off-white solid | ||
| Primary Target | MMP-1 | ||
| Primary Target Ki | 0.2 nM | ||
| Secondary target | Ki = 500 nM for MMP-2; Ki = 20 µM for MMP-3; Ki = 100 nM for MMP-8; and Ki = 100 nM for MMP-9 | ||
| Molar mass | 463.6 | ||
| Purity | ≥95% by HPLC | ||
| Solubility | DMSO | ||
| Chemical formula | C27H33N3O4 | ||
| CAS number | 170905-75-6 | ||
| Store and ship information | |||
|---|---|---|---|
| Storage | -20°C | ||
| Ship |
Ambient Temperature Only
Standard Handling |
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