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317630  Dipeptidylpeptidase IV, Human Placenta

CD26, DPPIV

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25 May 2012

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Kindly contact Customer Service to order this product.

This product has been discontinued.

We are offering Dipeptidylpeptidase IV, His•Tag®, Human, Recombinant, S. frugiperda (Cat. No. 317639) or Dipeptidyl Peptidase IV (CD26), Porcine Kidney (Cat. No. 317640) as a possible alternative. Please read the alternative product documentation carefully and contact technical service if you need additional information.





Native DPP-IV purified from human placenta. DPP-IV is a serine exopeptidase dimer composed of two identical subunits of 110-130 kDa. DPP-IV is involved in many cellular processes such as activation of cytokines, differentiation, and cell-matrix interactions. Inhibition of DPP-IV has been reported to be an effective treatment for type II diabetes. MW: ~220000-260000 (unreduced) Note: 1 MIU = 1 milliunit.
Product information
Form Lyophilized
Formulation Lyophilized from 2 mM Tris buffer, pH 8.0
Molar mass 220000
Avoid freeze/thaw Yes
Specific activity ≥10 U/mg
Unit definition One unit is defined as the amount of enzyme that will hydrolyze 1 µmole H-Gly-Pro-pNA per min at room temperature, pH 8.0.
Purity ≥95% by SDS-PAGE
Source Prepared from tissue that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV-1, HIV-2, HBsAg, and HCV.
Solubility H2O
EC number 3.4.14.5
Store and ship information
Storage -20°C
Ship Blue Ice Only
Standard Handling

© Merck KGaA, Darmstadt, Germany, 2012

All references to Merck refer to Merck KGaA, Darmstadt, Germany.


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