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252750  Deferoxamine Mesylate

Desferrioxamine Mesylate, DFOM

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25 May 2012

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252750-1GM  1 gm 
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Parenteral iron chelating agent. Commonly used in therapy as a chelator of ferric iron in disorders of iron overload. Completely protects against dopamine-induced cell death. Has also been shown to interfere with hydroxyl radical formation, which mediates tissue damage in several disease states. Shows anti-proliferative effect on vascular smooth muscle cells in vitro and in vivo. Can also inhibit the oxidative chemistry of peroxynitrite by reaction of the hydroxamic acid moieties with trans-peroxynitrous acid.
Product information
Form White powder with a faint yellow cast
Molar mass 656.8
Hygrocopic Yes
Purity 92.5-100% by TLC
Solubility H2O
Chemical formula C25H48N6O8·CH4O3S
RTECS UG5310000
CAS number 138-14-7
Merck USA index 14, 2860
Store and ship information
Storage +2°C to +8°C
Ship Ambient Temperature Only
Harmful & Carcinogenic / Teratogenic
Safety information
S Phrase S: 22-26-36

Do not breathe dust.
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
Wear suitable protective clothing.
R Phrase R: 22-36/37/38-40-42/43

Harmful if swallowed.
Irritating to eyes, respiratory system and skin.
Limited evidence of a carcinogenic effect.
May cause sensitization by inhalation and skin contact.
Deferoxamine Mesylate, molecular structure

© Merck KGaA, Darmstadt, Germany, 2012

All references to Merck refer to Merck KGaA, Darmstadt, Germany.


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