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EMD Millipore
290 Concord Road
01821 Billerica, MA
United States
Phone: 781 533-6000
Fax: +49 6151 72 2000
E-mail: Customer.CareDesk@emdchemicals.com
25 May 2012
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Potent cell-permeable anticancer agent whose potential target site may be mitochondrial cytochrome c oxidase. Has been shown to inhibit RNA and DNA synthesis. Inhibits eukaryotic topoisomerases I and II. Induces DNA single-strand breaks. Also induces apoptosis in HeLa S3 tumor cells.
| Product information | |||
|---|---|---|---|
| Form | Red crystalline solid | ||
| Primary Target | DNA synthesis, RNA synthesis | ||
| Molar mass | 564.0 | ||
| Hygrocopic | Yes | ||
| Cell permeable | Yes | ||
| Purity | Potency: ≥840 µg/mg | ||
| Solubility | H2O | ||
| Chemical formula | C27H29NO10 · HCl | ||
| RTECS | HB7878000 | ||
| CAS number | 23541-50-6 | ||
| Merck USA index | 14, 2832 | ||
| Store and ship information | |||
|---|---|---|---|
| Storage | +15°C to +30°C | ||
| Ship |
Ambient Temperature Only
Harmful & Carcinogenic / Teratogenic |
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| Safety information | |||
|---|---|---|---|
| S Phrase |
S: 22-36/37-45 Do not breathe dust. Wear suitable protective clothing and gloves. In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible). |
||
| R Phrase |
R: 22-40-42/43 Harmful if swallowed. Limited evidence of a carcinogenic effect. May cause sensitization by inhalation and skin contact. |
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