For general questions please contact our Customer Service:
EMD Millipore
290 Concord Road
01821 Billerica, MA
United States
Phone: 781 533-6000
Fax: +49 6151 72 2000
E-mail: Customer.CareDesk@emdchemicals.com
25 May 2012
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Recombinant, mouse COCO, consisting of amino acids 24-185 and expressed in E. coli. COCO, a member of the DAN Domain family of BMP antagonists, is able to bind to Xnr1, BMP-4, activin, and Wnt8.
| Product information | |||
|---|---|---|---|
| Form | Solid | ||
| Formulation | Lyophilized from 0.2 µm filter-sterilized Acetonitrile, TFA, and BSA. | ||
| Biological activity | ED50 = 0.6-3 µg/ml as determined by inhibition of BMP-4-induced activity (50 ng/ml BMP-4) in MC3T3-E1 mouse osteoblastic cells. | ||
| Purity | ≥90% by SDS-PAGE | ||
| Contaminants | Endotoxin: <1.0 EU/µg protein | ||
| Store and ship information | |||
|---|---|---|---|
| Storage | -20°C | ||
| Ship |
Ambient Temperature Only
Standard Handling |
||
