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233165  Clioquinol

5-Chloro-7-iodo-8-hydroxyquinoline

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25 May 2012

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233165-1GM  1 gm 
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A metal ion chelator that crosses the blood brain barrier and acts as a neurotoxic antibiotic. Reported to dissolve senile plaques and reduce amyloid’s ability to clump together, apparently by trapping the Cu2+ and Zn2+ that stud these deposits. Shown to increase distal dominant axonopathy in animal models.
Product information
Form Solid
Molar mass 305.5
Protect from Light Yes
Packaged under inert gas Yes
Purity ≥95% by HPLC
Solubility DMSO, EtOH or MeOH
Chemical formula C9H5ClINO
RTECS VC5075000
CAS number 130-26-7
Merck USA index 14, 5031
Store and ship information

Hazardous Materials Attention: Due to the nature of the Hazardous Materials in this shipment, additional shipping chargesmay be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.

Storage -20°C
Ship Ambient Temperature Only
Toxic & Carcinogenic / Teratogenic
Safety information
S Phrase S: 26-36

In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
Wear suitable protective clothing.
R Phrase R: 42/43-63

May cause sensitization by inhalation and skin contact.
Possible risk of harm to the unborn child.
Clioquinol, molecular structure

© Merck KGaA, Darmstadt, Germany, 2012

All references to Merck refer to Merck KGaA, Darmstadt, Germany.


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