203292
Bisindolylmaleimide II
2-[1-[2-(1-Methylpyrrolidino)ethyl]-1H-indol-3-yl]-3-(1H-indol-3-yl)maleimide
For general questions please contact our Customer Service:
EMD Millipore
290 Concord Road
01821 Billerica, MA
United States
Phone: 781 533-6000
Fax: +49 6151 72 2000
E-mail: Customer.CareDesk@emdchemicals.com
25 May 2012
loading
A potent, cell permeable, reversible, ATP-competitive and selective inhibitor of protein kinase C (IC50 = 13 nM). May inhibit protein kinase A at much higher concentrations (IC50 = 2 µM).
| Product information | |||
|---|---|---|---|
| Form | Orange solid | ||
| Primary Target | PKC | ||
| Primary Target IC50 | 13 nM | ||
| Secondary target | PKA (IC50 = 2 mM) | ||
| Molar mass | 438.5 | ||
| Cell permeable | Yes | ||
| Purity | ≥95% by HPLC | ||
| Solubility | DMSO | ||
| Chemical formula | C27H26N4O2 | ||
| CAS number | 137592-45-1 | ||
| Store and ship information | |||
|---|---|---|---|
| Storage | +2°C to +8°C | ||
| Ship |
Ambient Temperature Only
Standard Handling |
||
