286890
BH3I-1
5-(p-Bromobenzylidine)-α-isopropyl-4-oxo-2-thioxo-3-thiozolidineacetic Acid
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EMD Millipore
290 Concord Road
01821 Billerica, MA
United States
Phone: 781 533-6000
Fax: +49 6151 72 2000
E-mail: Customer.CareDesk@emdchemicals.com
25 May 2012
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This product has been discontinued.
Please refer to our complete listing of apoptosis inducers for possible alternatives. Please read the alternative product documentation carefully and contact technical service if you need additional information.
A novel cell-permeable BH3 mimetic that induces apoptosis by specifically preventing BH3 domain-mediated interaction between pro-apoptotic and anti-apoptotic members of the Bcl-2 family (Ki = 2.4 - 7.8 µM). Inhibits the binding of Bak BH3 peptide to Bcl-xL (Ki = 2.4 - 7.8 µM) by targeting the BH3 binding pocket of Bcl-xL.
| Product information | |||
|---|---|---|---|
| Form | Yellow solid | ||
| Molar mass | 400.3 | ||
| Protect from Light | Yes | ||
| Packaged under inert gas | Yes | ||
| Purity | ≥95% by HPLC | ||
| Solubility | DMSO | ||
| Chemical formula | C15H14BrNS2O3 | ||
| Store and ship information | |||
|---|---|---|---|
| Storage | -20°C | ||
| Ship |
Ambient Temperature Only
Harmful |
||
| Safety information | |||
|---|---|---|---|
| S Phrase |
S: 36 Wear suitable protective clothing. |
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| R Phrase |
R: 20/21/22 Harmful by inhalation, in contact with skin and if swallowed. |
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