171591
β-Amyloid Peptide (1-40), Human, Fluorescent-Labeled
DAC-Aβ1-40, Human
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EMD Millipore
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25 May 2012
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An N-terminally modified human Aβ1-40 peptide labeled with a fluorophore, 7-diethylaminocoumarin-3-carbonyl (DAC) that shares a common binding site with Aβ1-40 (Cat. No. 171590) with 40-fold greater affinity. Displays stronger affinity towards GM1-ganglioside and cholesterol containing membranes but little affinity for phospholipids. Exhibits only a weak fluorescence in aqueous medium; however, it strongly fluoresces upon binding to membranes. Useful in assessing the binding affinity of Aβ for various membranes.
| Product information | |||
|---|---|---|---|
| Form | Lyophilized | ||
| Formulation | Supplied as a trifluoroacetate salt. | ||
| Molar mass | 4573.1 | ||
| Protect from Light | Yes | ||
| Hygrocopic | Yes | ||
| Packaged under inert gas | Yes | ||
| Purity | ≥95% by HPLC | ||
| Excitation max. | 430 nm | ||
| Emission max. | 470 nm | ||
| Solubility | 25% Acetic Acid or DMSO | ||
| Chemical formula | C208H308N54O61S | ||
| Store and ship information | |||
|---|---|---|---|
| Storage | ≤ -70°C | ||
| Ship |
Ambient Temperature Only
Standard Handling |
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