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176904  Anthrax Lethal Factor Protease Substrate III, Fluorogenic

Anthrax LF Protease Substrate III, Fluorogenic, Bacillus anthracis LF Protease Substrate III, Fluorogenic

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25 May 2012

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176904-1MG  1 mg 
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An N-acetylated, C-7-amido-4-methylcoumarin (AMC) derivative of a 14-mer peptide substrate designed from the MEK-2 template that is useful for measuring Anthrax lethal factor (LF) metalloproteolytic activity with a detection limit of ~5-10 pM. Reported to be useful for high-throughput screening of LF inhibitors.
Product information
Peptide Sequence Ac-Gly-Tyr-βAla-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Val-Leu-Arg-AMC
Form Lyophilized
Formulation Supplied as a trifluoroacetate salt.
Molar mass 2126.5
Protect from Light Yes
Hygrocopic Yes
Packaged under inert gas Yes
Purity ≥97% by HPLC
Excitation max. ~360 nm
Emission max. ~460 nm
Solubility DMSO
Chemical formula C91H156N42O18
Store and ship information
Storage -20°C
Ship Blue Ice Only
Standard Handling

© Merck KGaA, Darmstadt, Germany, 2012

All references to Merck refer to Merck KGaA, Darmstadt, Germany.


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