For general questions please contact our Customer Service:
EMD Millipore
290 Concord Road
01821 Billerica, MA
United States
Phone: 781 533-6000
Fax: +49 6151 72 2000
E-mail: Customer.CareDesk@emdchemicals.com
25 May 2012
loading
Kindly contact Customer Service to order this product.
This product has been discontinued.
We are offering Angiostatin K1-3, Human, Recombinant, P. pastoris (Cat. No. 176708) as a possible alternative. Please read the alternative product documentation carefully and contact technical service if you need additional information.
A proteolytic fragment of plasminogen constituting kringles 1 - 4. A specific inhibitor of endothelial cell proliferation and one of the most potent and specific natural inhibitors of angiogenesis and metastatic tumor growth. Human angiostatin significantly inhibits bFGF-induced endothelial cell proliferation and migration at concentrations ranging from 300 nM - 1.0 µM.
| Product information | |||
|---|---|---|---|
| Form | Lyophilized | ||
| Formulation | Lyophilized from 40 mM NaCl, 20 mM HEPES-NaOH, pH 8.0. | ||
| Molar mass | 50,000 | ||
| Purity | ≥98% by SDS-PAGE (migrates as a doublet) | ||
| Contaminants | plasmin, plasminogen: none detected | ||
| Source | Prepared from fluid that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV. | ||
| Solubility | H2O | ||
| RTECS | BW2140000 | ||
| CAS number | 86090-08-6 | ||
| Declaration | Sold under license of U.S. Patent 6,024,688 and corresponding patents. | ||
| Store and ship information | |||
|---|---|---|---|
| Storage | DEEP FREEZE (-70°C) | ||
| Ship |
Dry Ice Only
Standard Handling |
||
