128135
Aloisine, RP106
RP106, 7-n-Butyl-6-(4-methoxyphenyl)[5H]pyrrolo[2,3-b]pyrazine
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EMD Millipore
290 Concord Road
01821 Billerica, MA
United States
Phone: 781 533-6000
Fax: +49 6151 72 2000
E-mail: Customer.CareDesk@emdchemicals.com
25 May 2012
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A cell-permeable pyrrolo-pyrazine compound that exerts anti-proliferative effects. Acts as a potent, selective, ATP-competitive inhibitor of CDK1/cyclin B, CDK5/p25, and GSK-3 (IC50 = 700 nM, 1.5 µM, and 920 nM, respectively).
| Product information | |||
|---|---|---|---|
| Form | Cream-colored solid | ||
| Primary Target | Cdkl1, Cdkl5, GSK-3 | ||
| Primary Target IC50 | 700 nM, 1.5 µM, 920 µM | ||
| Molar mass | 281.4 | ||
| Protect from Light | Yes | ||
| Packaged under inert gas | Yes | ||
| Cell permeable | Yes | ||
| ATP Competitive | Yes | ||
| Purity | ≥95% by HPLC | ||
| Solubility | DMSO or MeOH | ||
| Chemical formula | C17H19N3O | ||
| CAS number | 496864-15-4 | ||
| Store and ship information | |||
|---|---|---|---|
| Storage | +2°C to +8°C | ||
| Ship |
Ambient Temperature Only
Standard Handling |
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