658430
AG 99
Tyrphostin A46, Tyrphostin B40, α-Cyano-(3,4-dihydroxy)cinnamide
For general questions please contact our Customer Service:
EMD Millipore
290 Concord Road
01821 Billerica, MA
United States
Phone: 781 533-6000
Fax: +49 6151 72 2000
E-mail: Customer.CareDesk@emdchemicals.com
25 May 2012
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This product has been discontinued.
Please refer to our complete listing of protein tyrosine kinase inhibitors for possible alternatives. Please read the alternative product documentation carefully and contact technical service if you need additional information.
A cell-permeable, reversible, and substrate competitive inhibitor of epidermal growth factor (EGF) receptor tyrosine kinase (IC50 = 10 µM) and EGF-dependent cell proliferation. Inhibits EGFR phosphorylation and ERK1 and ERK2 activities.
| Product information | |||
|---|---|---|---|
| Form | Off-white solid | ||
| Primary Target | epidermal growth factor (EGF) receptor tyrosine kinase | ||
| Primary Target IC50 | 10 µM | ||
| Secondary target | EGF-dependent cell proliferation, EGFR phosphorylation and ERK1 and ERK2 activities | ||
| Molar mass | 204.2 | ||
| Protect from Light | Yes | ||
| Purity | ≥95% by HPLC | ||
| Solubility | DMSO | ||
| Chemical formula | C10H8N2O3 | ||
| CAS number | 118409-59-9 | ||
| Store and ship information | |||
|---|---|---|---|
| Storage | -20°C | ||
| Ship |
Ambient Temperature Only
Standard Handling |
||
