658402
AG 527
(-)-(R)-N-(α-Methylbenzyl)-3,4-dihydroxybenzylidinecyanoacetamide, α-Cyano-(-)-(R)-N-(α-phenethyl)-3,4-dihydroxycinnamide, Tyrphostin B44(-)
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EMD Millipore
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25 May 2012
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A cell-permeable, reversible, and substrate competitive inhibitor of epidermal growth factor (EGF) receptor kinase autophosphorylation (IC50 = 2.5 µM). Also inhibits phosphorylation of poly-GAT by the EGF receptor (IC50 = 400 nM).
| Product information | |||
|---|---|---|---|
| Form | Yellow solid | ||
| Primary Target | epidermal growth factor (EGF) receptor kinase autophosphorylation | ||
| Primary Target IC50 | 2.5 µM | ||
| Secondary target | phosphorylation of poly-GAT by the EGF receptor (IC50 = 400 nM) | ||
| Molar mass | 308.3 | ||
| Protect from Light | Yes | ||
| Purity | ≥98% by HPLC | ||
| Solubility | DMSO or EtOH | ||
| Chemical formula | C18H16N2O3 | ||
| CAS number | 133550-32-0 | ||
| Store and ship information | |||
|---|---|---|---|
| Storage | -20°C | ||
| Ship |
Ambient Temperature Only
Standard Handling |
||
