658553
AG 1433
2-(3,4-Dihydroxyphenyl)-6,7-dimethylquinoxaline, HCl, SU 1433, VEGFR Tyrosine Kinase Inhibitor IX, VEGFR2 Kinase Inhibitor XI
For general questions please contact our Customer Service:
EMD Millipore
290 Concord Road
01821 Billerica, MA
United States
Phone: 781 533-6000
Fax: +49 6151 72 2000
E-mail: Customer.CareDesk@emdchemicals.com
25 May 2012
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A potent, cell-permeable, reversible, and specific inhibitor of the PDGF-β receptor kinase (IC50 = 5.0 µM) and of KDR/Flk-1/VEGF Receptor 2 (IC50 = 9.3 µM). Also acts as an angiogenesis inhibitor.
| Product information | |||
|---|---|---|---|
| Form | Pale brown solid | ||
| Primary Target | PDGF-β receptor kinase | ||
| Primary Target IC50 | 5 µM | ||
| Secondary target | KDR/Flk-1/VEGF Receptor 2 (IC50 = 9.3 µM). Also acts as an angiogenesis inhibitor. | ||
| Molar mass | 302.8 | ||
| Protect from Light | Yes | ||
| Packaged under inert gas | Yes | ||
| Purity | ≥95% by HPLC | ||
| Solubility | DMSO | ||
| Chemical formula | C16H14N2O2 · HCl | ||
| CAS number | 168836-03-1 | ||
| Store and ship information | |||
|---|---|---|---|
| Storage | -20°C | ||
| Ship |
Ambient Temperature Only
Standard Handling |
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