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116813  Adenosine 3′,5′-cyclic Monophosphorothioate, 8-Bromo-2′-monobutyryl-, Rp-Isomer, Sodium Salt

Rp-8-Br-MB-cAMPS, Na

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25 May 2012

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A cell-permeable and reversible inhibitor of protein kinase A that is reported to block the excitatory effect of 8-Bromo-cGMP and to inhibit the basal Ca2+ currents in smooth muscle. More lipophilic and cell permeable than Rp-8-Bromo-cAMP (Cat. No. 116816). Note: 5 µmol = 2.58 mg.
Product information
Form White lyophilized solid
Primary Target PKA
Secondary target Basal Ca2+ current in smooth muscle
Molar mass 516.2
Hygrocopic Yes
Cell permeable Yes
Purity ≥97% by HPLC
Solubility H2O
Chemical formula C14H16BrN5O6PS · Na
Declaration Sold under license of Patent DE 3,802,865.4 issued to BIOLOG LSI.
Store and ship information
Storage -20°C
Ship Ambient Temperature Only
Standard Handling
Adenosine 3′,5′-cyclic Monophosphorothioate, 8-Bromo-2′-monobutyryl-, Rp-Isomer, Sodium Salt, molecular structure

© Merck KGaA, Darmstadt, Germany, 2012

All references to Merck refer to Merck KGaA, Darmstadt, Germany.


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