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EMD Millipore
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25 May 2012
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A cell-permeable inhibitor of phospholipase A2 that blocks epinephrine-stimulated thromboxane production in platelets. Inhibits ATP-stimulated phosphatidylcholine (PC) secretion in alveolar type II cells. Also blocks phorbol ester and A23187-induced PC secretion in type II cells. Reported to block glucose-induced insulin secretion by pancreatic β-cells. Exhibits moderate leukotriene antagonist activity.
| Product information | |||
|---|---|---|---|
| Form | White solid | ||
| Primary Target | A2PLA2 | ||
| Molar mass | 337.4 | ||
| Protect from Light | Yes | ||
| Cell permeable | Yes | ||
| Purity | ≥99% by TLC | ||
| Solubility | DMSO or EtOH | ||
| Chemical formula | C21H23NO3 | ||
| CAS number | 110683-10-8 | ||
| Store and ship information | |||
|---|---|---|---|
| Storage | +15°C to +30°C | ||
| Ship |
Ambient Temperature Only
Standard Handling |
||
