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100122  A3, Hydrochloride

N-(2-Aminoethyl)-5-chloronaphthalene-1-sulfonamide, HCl

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25 May 2012

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100122-10MG  10 mg 
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Prices are subject to change without notice.
A cell-permeable, reversible, and shorter alkyl chain derivative of W-7 that inhibits casein kinase I (Ki = 80 µM), casein kinase II (Ki = 5.1 µM), myosin light chain kinase (Ki = 7.4 µM), protein kinase A (Ki = 4.3 µM), protein kinase C (Ki = 47 µM), and protein kinase G (Ki = 3.8 µM).
Product information
Form Off-white solid
Primary Target CK1
Primary Target Ki 80 µM
Secondary target CK2 (Ki = 5.1 µM), MLCK (Ki = 7.4 µM), PKA (Ki = 4.3 µM), PKC (Ki = 47 µM), PKG (Ki = 3.8 µM)
Molar mass 321.2
Hygrocopic Yes
Purity ≥98% by TLC
Solubility DMSO or 50% Ethanol
Chemical formula C12H13ClN2O2S · HCl
CAS number 78957-85-4
Store and ship information
Storage -20°C
Ship Ambient Temperature Only
Standard Handling
A3, Hydrochloride, molecular structure

© Merck KGaA, Darmstadt, Germany, 2012

All references to Merck refer to Merck KGaA, Darmstadt, Germany.


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