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Technical Notes about ZIC®-HILIC

Summaries of scientific papers including specific conditions for separation using SeQuant® ZIC®-HILIC columns

SeQuant® scientists have summarized scientific papers featuring the use of ZIC®-HILIC columns to provide you with a convenient 2 page overview of the complete experimental conditions used to separate a particular compound(s). For a list of links to articles published by scientists using SeQuant® products to solve difficult analysis problems in laboratories around the world, visit our Scientific Papers page.

We take pride in helping to support your research success and encourage you to share your experience as we continuously strive to expand and share this resource collection.

Don’t see information about purification of your compound? Check our complete collection of technical support resources or try using our online HILIC Retention Prediction Tool. Just enter your molecular formula to determine the optimal conditions for purification on ZIC®-HILIC columns.

Visit our on-line tutorial to learn more about HILIC technology or request our comprehensive „A Practical Guide to HILIC“ booklet. Both provide detailed explanations of technology and techniques to ensure your success using EMD Millipore’s innovative SeQuant® ZIC®-HILIC products


If you still can’t find the information you need, you can always contact the SeQuant® Support Team who are happy to assist you.

 

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Determination of Paralytic Shellfish Poisoning Toxins via ZIC-HILIC and MSMS

Determination of Paralytic Shellfish Poisoning Toxins via ZIC®-HILIC and MS/MS

Paralytic shellfish poisoning toxins are very polar compounds that can be separated via a ZIC®-HILIC stationary phase. A straight-forward extraction procedure and a single separation allows for the determination of a broad range of compounds with excellent sensitivity over a wide concentration range.
A single run is capable of monitoring eighteen toxins with superb limits of detection (typically <0.5 ng, S/N = 3) and good linearity using a triple quadrupole mass spectrometer.


Technical Notes-summary of scientific papers

TN-001 Enhanced Resolution of Glucosinolates using ZIC-HILIC Chromatography (73 kB)

TN-002 ZIC-HILIC for Multidimensional Protein Identification Technology (MudPIT) (94 kB)

TN-003 Increasing the Sensitivity for Oseltamivir using ZIC-HILIC Chromatography (109 kB)

TN-004 Rapid Identification of Diethylene Glycol in a Mass Poisoning Epidemic using ZIC-HILIC Chromatography (98 kB)

TN-005 Quantification of Cisplatin via ZIC-HILIC Separation and On-line ICP-MS Detection (98 kB)

TN-006 Separation of Carbohydrate-related Metabolites from Leaf Tissue via ZIC-HILIC Chromatography and on-line Electrospray Mass Spectrometry (109 kB)

TN-007 Determination of Methylmalonic Acid in Plasma using ZIC-HILIC Chromatography and Single Stage Mass Spectrometric Detection (119 kB)

TN-008 Simultaneous Determination of Melamine and Cyanuric Acid in Animal Feed via ZIC-HILIC Chromatography - Mass Spectrometry (96 kB)

TN-009 Determination of Paralytic Shellfish Poisoning Toxins via ZIC-HILIC and MSMS (122 kB)


Technical Summaries: research topic area review written by an expert in the field

TS-001 Analysis of Protein Glycosylation Using HILIC

 

SeQuant® Applications    
  Applications by Topic Glycomics and Glycoproteomics
    Ion Analysis
    Melamine
    Peptide Mapping
    Sugar Analysis
  Application Notes  
  Scientific Papers  
  Technical Notes  

© Merck KGaA, Darmstadt, Germany, 2013

All references to Merck refer to Merck KGaA, Darmstadt, Germany.


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